Child Survival - Project HOPE is administering a child survival programme in the rural areas of the Jinotega Department. This programme aims to improve maternal and child health by improving the quality of care given to pregnant women, encouraging the timely seeking of services, and improving the knowledge and skills of pregnancy management at the community level. It also seeks to improve the nutritional status of children less than 5 years old by integrating nutritional counselling into all consultations with mothers to improve nutrition awareness and surveillance, as well micronutrient surveillance. Other interventions include breastfeeding promotion, improved immunisation coverage, control of diarrhoeal diseases and pneumonia cases, improved child spacing, and HIV/AIDS prevention education.

Primary Care Community Clinic - Project HOPE and its partner, MANNA Project International, seeks to establish a clinic in Managua, Nicaragua, based on the successful experiences implementing similar clinics in the Dominican Republic. This clinic will start out providing essential and specialised maternal and child healthcare, health education in the clinic and the community, home visits and vaccinations in coordination with the Ministry of Health, and general medical attention for adults.

Village Health Banks - Project HOPE is using its Village Health Bank model of combining micro-credit activity with health education to address issues of domestic violence. The goal is for approximately 2,000 women to participate along with their partners, indigenous organisations already working in domestic violence and law enforcement.